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A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.

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Enalapril other names for sialolactone are: sialinamide [11] sialolone fumarate, sialolol [15] sialoloid acid sialic acid is used in the treatment of angina pectoris, angina, angina-like chest pain/discomfort, asthma and bronchospasms, is sometimes used for the treatment of myocardial infarction, heart failure, and arteriovenous malformation. It is approved as an antiarrhythmic agent and antihyperglycemic agent. Some evidence suggests that sialic acid may reduce heart attacks in patients who are at high risk of having a heart attack.[15][16] In animal studies, sialic acid has effects on platelet aggregation and vasodilation, possibly mediated through calcium.[11] Uses Sialolactone is the generic name for a class of drugs called prodrugs, that are made from a precursor drug. Prohormone drugs are used as a precursor to sialophorin which is used as an agonist at progesterone receptors.[20][21] Sialolactone is used in the treatment of heart failure (including caused by any cause), is used to enhance the effectiveness of coronary block therapy, to accelerate wound healing, in postoperative pain, the treatment of pulmonary hypertension in children, and the treatment of angina pectoris. Prostaglandins are that involved in the formation of blood clots and vessel elasticity.[22] Sialolactone (sialic acid) is used as a potent vasodilator and an inhibitor of platelet aggregation.[23] Sialolactone is used as an antitumor agent in the treatment of cancers including ovarian cancer,[24] lung cancer, liver cervical colon pancreatic breast cancer (all forms), and other cancers.[25] It can cause hypotensive effects in patients under treatment for cardiac disease.[26] This has led to the use of less potent antidiuretics, such as atropine or thiazide, to minimize hypotension. Sialolactone is also used in the treatment of myocardial infarction in patients with a prior history of cardiac disease. The drug is available in a single tablet of 500mg containing 600mg sialolactone and 200mg sialostatin (2.0mg 0.9mg sodium sialostat). Sialolactone is more likely than sialopyridine to induce hypokalemia.[22][27] The sialostatin analogues dalcetrapib and etenolol also have been reported to antiarrhythmic and antihyperglycemic effects through sialolactone.[28][29][30] The drug has also become a treatment for pulmonary hypertension, which is a risk factor for cardiovascular disease.[31] Chemical structures Sialinamide is a molecular chiral molecule comprising hydrogen and oxygen atoms in the 4' region, as is case for wegmans pharmacy generic price list many progestins. The chemical structure of sialinamide has been determined by X-ray spectroscopy.[32] The molecule is a linear c